Definitely In!
I missed the last couple of Ludum Dares due to bad timing, my last was LD24, but I missed it and this one will most likely work out time wise!
I will most likely be using the Unity engine this time, with NGUI and 2d toolkit. SFXR for sound and either pickle or Pixel Art editor on my tablet for graphics.
All of the themes look really interesting and I look forward to using any of them I think.
Good luck everyone!