Brainstorming themes

I went ahead and looked through the final themes, and went ahead and wrote down at least one game idea for each. And I have to say that some are much easier to come up with a cool game/mechanics, and some are much more complicated.

My biggest struggles were: - Take one, leave one (very American theme, as I have not heard this phrase anywhere else) - One item, many uses - Sacrifices must be made - Break the cycle

The ones I had best fun coming up with ideas: - Magic, but at what cost? - Control the environment, not the player - Each play through builds on last - It only changes when you aren't looking

What are your thoughts, any themes you struggle with or enjoy?